LystMutation in Mice Recapitulates Iris Defects of Human Exfoliation Syndrome
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چکیده
منابع مشابه
Lyst mutation in mice recapitulates iris defects of human exfoliation syndrome.
PURPOSE Human eyes with exfoliation syndrome (XFS) exhibit a distinctive pattern of iris transillumination defects that are recapitulated in Lyst mutant mice carrying the beige allele. The purpose of this study was to determine the anatomic basis for Lyst-mediated transillumination defects, test whether Lyst mutant mice develop other features of XFS, and describe the molecular basis of the beig...
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Purpose To estimate the frequency of exfoliation syndrome (XFS) and its association with ocular diseases in Northern Nigeria. Materials and methods Consecutive patients who presented to the outpatient department of ECWA Eye Hospital Kano from February 2015 to May 2015 were included in the study. Each patient had a complete ophthalmic examination. The anterior segment examination included tono...
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The study cohort consists of 459 subjects over 60 years of age. Intraocular pressure and degrees of exfoliation, lens changes, and pigment were recorded and their interrelationships investigated. A raised intraocular pressure was found to be associated with exfoliation, as also was increased pigmentation and the development of lens changes. An original observation is that the exfoliated males h...
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In the Eye Outpatient Department of H.P. Medical College Hospital, Simla, nine cases of capsular exfoliation affecting seventeen eyes were seen in the course of 6 months. Their main features are given in Table I (overleaf, pp. I22 and 123). All the patients were males between the ages of 6o and 76 years. The capsular exfoliation was associated with phakodonesis, iridodonesis, glaucoma, primary ...
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ژورنال
عنوان ژورنال: Investigative Opthalmology & Visual Science
سال: 2009
ISSN: 1552-5783
DOI: 10.1167/iovs.08-2791